2018 22:835вЂ“42.Д«rantsma AH, Bakker SJ, de Zeeuw D, de Jong PE, Gansevoort RT. High-normal albuminuria and incident chronic kidney disease in a male nondiabetic population. 2019 23:1вЂ“15.ДЄshitani A, Ueno T, Nakashima A, Doi S, Yamane K, Masaki T. Essential points from evidence-based Clinical Practice Guidelines for Chronic Kidney Disease 2018. In conclusion, the results of the present study indicated that salt-induced albuminuria was enhanced in subjects with higher drinking frequency, suggesting that salt restriction may have a stronger renoprotective effect in subjects with higher drinking frequency.ДЄlbuminuria Alcohol drinking Salt intake. The association between в€†salt intake and в€†Log UACR was enhanced by drinking frequency in a dose-dependent manner (per 1 g/day of в€†salt intake, adjusted Гџ 0.13, 0.16, and 0.20 in rare, occasional, and daily drinkers, respectively). A multivariable-adjusted linear regression model showed a significant association between в€†salt intake and в€†Log UACR (per 1 g/day of в€†salt intake, adjusted Гџ 0.16 ) and an effect modification between drinking frequency and в€†salt intake (P for interaction = 0.088). To assess the association between the changes in salt intake and albuminuria, the differences in salt intake estimated from single-spot urine specimens and the urinary albumin-to-creatinine ratio (UACR) between 20 were calculated for each subject. The main exposure of interest was drinking frequency at their first checkups categorized as rarely, occasionally, and daily. Overall, 448 employees at a pharmaceutical company in Japan who underwent annual health checkups in both 20 were evaluated. This 1-year observational study aimed to assess the effect modification of alcohol drinking on the association between salt intake and albuminuria. Albuminuria is an important risk factor for end-stage kidney disease and cardiovascular mortality.

Ryuichi yamamoto